Concurrent sequence variation of TP53 and TP73 genes in anaplastic astrocytoma
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چکیده
منابع مشابه
Concurrent sequence variation of TP53 and TP73 genes in anaplastic astrocytoma.
Disruption or loss of tumor suppressor gene TP53 is implicated in the development or progression of almost all different types of human malignancies. Other members of the p53 family have been identified. One member, p73, not only shares a high degree of similarity with p53 in its primary sequence, but also has similar functions. Like p53, p73 can bind to DNA and activate transcription. Using PC...
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ژورنال
عنوان ژورنال: Genetics and Molecular Research
سال: 2009
ISSN: 1676-5680
DOI: 10.4238/vol8-4gmr631